USE OF DIRECT ORAL ANTICOAGULANTS FOR THE PREVENTION AND TREATMENT OF THROMBOEMBOLIC DISEASE IN PATIENTS WITH REDUCED RENAL FUNCTION: A SHORT REVIEW OF THE CLINICAL EVIDENCE

Kristine C Willett, Amanda M Morrill Department of Pharmacy Practice, School of Pharmacy, MCPHS University, Manchester, NH, USA Background: The use of direct oral anticoagulants (DOACs) is restricted by the limitations of clinical trials guiding therapy for patients with renal impairment, as many of these trials excluded patients with severe renal

In the presence of conducting inhomogeneities in near-surface structures, apparent resistivity data in magnetotelluric sounding can be severely distorted.This is due to electric fields generated from boundary charges on surficial inhomogeneities.Such distortion persists throughout the entire recording range and is known as static shift in magnetote

Abstract The application of thermodynamic reasoning in the study of learning systems has a long tradition.Recently, new tools relating perfect thermodynamic adaptation to the adaptation process have been developed.These results, known as fluctuation theorems, have been tested experimentally in several physical scenarios and, moreover, they have bee

Abstract Effect of negatively charged dust on resistive instability corresponding to the electrostatic wave is investigated in a Hall thruster plasma when this purely azimuthal wave is tilted and strong axial component of wave vector is developed.Analytical calculations are done to obtain the relevant dispersion equation, which is solved numericall